Epigenetic aberrations of gene expression in a rat model of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is mostly triggered by environmental and life-style factors and may involve epigenetic aberrations.However, a comprehensive documentation of the link between the dysregulated epigenome, transcriptome, and liver carcinogenesis is lacking.In the present study, Fischer-344 rats Banana were fed a choline-deficient (CDAA,